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Alzheimer's Prevention Clinic

A New Approach to Alzheimer's Disease Management

Alzheimer's disease doesn't just affect the patient; it affects the entire family. The Alzheimer's Prevention Clinic (APC) at Weill Cornell Medicine and NewYork-Presbyterian was founded in 2013 by Dr. Richard Isaacson, who has several family members affected.

The clinic focuses on cutting-edge prevention strategies & comprehensive education for the whole family. To schedule a visit call 212-746-0226 or email, or to learn more PDF iconView Our Brochure.

Learn About Alzheimer's Prevention Online Now:

To learn about steps you can take NOW to reduce your risk, and the latest Alzheimer's information, visit our patient, caregiver and family education site, This site includes a free online course about everything one needs to know about AD, plus many activities and resources. Featured on, NBC Today Show, and Dr. Oz.

NEWS: 2018 Fundraising Campaign

You can make a difference in the fight against Alzheimer's. 100% of our gift is tax deductable - to learn more, call Trish at 212-746-0226 or email Our campaign focuses on 4 key areas:

1) Women's research

2) Men's Brain Health program


4) Whoop biosensor research

Clinic overview:

People interested in lowering their Alzheimer's risk are followed over time and receive a personalized plan based on many elements, such as risk factors, genes, medical conditions, and the latest scientific research. Patients are cared for using a sophisticated and interactive state-of-the-art research tool and database. This approach allows for ongoing monitoring and development of personalized therapeutic options aimed at reducing risk and providing optimal care. To schedule a visit, call 212-746-0226.

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Please read the following to learn about Our Philosophy of Care and Frequently Asked Questions.

Our Philosophy

Alzheimer’s disease (AD) starts in the brain 20 to 30 years before the onset of symptoms, giving physicians ample time to intervene in an individualized fashion for those as risk. There is no "magic pill" or "magic cure" for AD treatment or prevention; however, combining a variety of strategies based on strong science and safety may yield the best chance for benefit. 

Our approach is based on a collaborative care model for Alzheimer's disease, while being firmly grounded in the latest scientific evidence-based therapies. This integrated approach to care aims to provide the most comprehensive therapies for patients with Alzheimer’s disease, mild cognitive impairment due to Alzheimer's, "preclinical" Alzheimer's, and patients who are at risk for the disease.

Personalized Medicine & Personalized Nutrition

We use the latest scientific evidence and consider a variety of factors — such as current and past medical problems, genetics, and nutritional patterns — to tailor therapies for each patient. These principles (also referred to as "pharmacogenomics" and "nutrigenomics") form the core of our APC approach. We emphasize lifestyle and nutritional approaches and collect data to help further the scientific study of the effects of dietary modifications on brain health.

Requirements for APC Participation

Alzheimer's Prevention

All patients who would like a consultation for Alzheimer's prevention and/or enrollment in the APC Brain Healthy Lifestyle Program should be under the care of a primary care physician and follow up with the APC at least every 6-12 months. Patients must send copies of all recent physician office notes and laboratory and radiology results — including brain imaging results (such as MRI or CT scans, if available) — and have actual radiology images on a CD-ROM mailed to the clinic at least 4 weeks before the appointment. Most insurance plans are accepted.

Visit Length

Patients who visit the APC will receive at least one hour of direct contact with the treating clinical team (Neurologist and/or Nurse Practicioner). Combined family education on Alzheimer's prevention may be provided, as well as individualized education and counseling. Please note: spouses, partners, and caregivers are welcome, but only those registered as patients will receive personalized medical advice.

For more information, or to schedule an appointment, please call 212-746-0226

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Our Supporters & Donate Now

We are extremely thankful to our grateful patients and family members, and the foundations, institutions and corporate partners that have helped advance the mission of our Alzheimer's Prevention Clinic, led by Dr. Isaacson.

You can donate online now. 100% of your tax-deductable donations go to support this groundbreaking research. To donate via check or for foundation support, contact Tom Horton at 212-746-4599 or email noting the Alzheimer's Prevention Clinic Fund.

Our Fall 2017 campaign covers 4 focus areas: 1) Women's research; 2) Men's Brain Health Program; 3); and 4) Whoop biosensor research. To learn more, call Trish Irizarry at 212-746-0226 or email

Supporter Spotlight (2017):

The 4th annual 'Memories for Mary' event took place in Tuscon, Arizona, founded by Mr. David Twardock in honor of his Mom. We are so appreciative of the gracious support of our Alzheimer's research program. Hosted at the Dove Mountain Golf Club and Resort, attendees have raised over $200,000 to help fast forward our work.

Thanks to this support, we can fund cutting-edge research (such as Alzheimer's Universe) with results published in the Journal of the Prevention of Alzheimer's Disease and presented at research conferences around the world. 

For more information, please call 212-746-0226


What should I expect when I schedule a consultation at the APC?

Patients who visit the APC will receive at least one hour of direct contact with the treating clinical team (Neurologist and/or Nurse Practicioner). Your provider will review past medical history, family history, medications, prior doctor notes/lab results, etc and make specific recommendations regarding AD risk reduction. In most cases, the clinician will order a panel of laboratory and other studies (possibly including genetic tests). While there is no one clear genetic test that can clearly predict if a person will develop AD, the clinician may use these results (as well as past medical problems, nutritional patterns, etc) to tailor therapies for each patient. These principles (also referred to as “pharmacogenomics” and “nutrigenomics”) form the core of our APC approach. Combined family education on AD treatment and prevention may be provided, as well as individualized education and counseling. Please note: spouses, partners, children and caregivers are of course welcome, but only those registered as patients will receive personalized medical advice. Multiple visits for separate family members during the same day are welcome, as we evaluate a wide range of patients (ranging from ~30s to 80s). PDF iconView Our Clinic Brochure and learn more.

What happens after the appointment?

Depending on the types of studies ordered, it usually takes several weeks or more for the specialized results to return. Follow-up appointments may be scheduled and vary, with the first follow-up occurring after 6-8 weeks, and subsequent visits every 6 - 12 months. Even for those visiting from out-of-town, discussion of test results and follow-up advice is necessary with an in-person follow-up visit, rather than via telephone.

What types of research is available?

While the core of the clinic visit is to discuss and recommend specific brain-healthy strategies that may help to delay the onset of (or possibly reduce risk) for memory loss and/or AD, or more optimally treat AD, patients will have the option to participate in an ongoing research study. This study aims to track the effect of different lifestyle changes on brain and body health. Currently, the Weill Cornell Memory Disorders Program is participating in a variety of studies in the area of AD prevention & treatment.

How can I make an appointment and what insurance plans are accepted?

Please call 212-746-0226. Most insurance plans are accepted. If you do not currently have insurance, a flat fee for appointments is available. PDF iconClick here to visit our Travel Tips and Suggestions for our out-of-town visitors.

Can Alzheimer’s be cured or 100% definitively prevented?

No, currently there are no known cures for AD, nor are there 100% definitive ways to prevent AD. The goal of the APC is to inform patients and their family members about the variety of strategies (based on strong science and balanced with safety) that may yield the best chance to treat AD, or possibly delay its onset. Through research, we hope to more definitively be able to guide our patients toward the most comprehensive ways to fight AD. All patients evaluated in the APC will have streamlined access to their physicians, including telephone access to the treating physician during office hours as questions arise. We believe that a personalized approach with open and direct access to the clinic physician and clinic staff ensures optimal care and may lead to the best patient outcomes.

Click to PDF iconView Our Clinic Brochure  or PDF iconView Our Travel Tips & Suggestions

For more information, or to schedule a consultation, please call 212-746-0226

Upper East Side 428 East 72nd Street, Suite 500 New York, NY 10021