Alzheimer's Prevention Education: If We Build It, Will They Come?

TitleAlzheimer's Prevention Education: If We Build It, Will They Come?
Publication TypeJournal Article
Year of Publication2014
AuthorsIsaacson RS, Haynes N, Seifan A, Larsen D, Christiansen S, Berger JC, Safdieh JE, Lunde AM, Luo A, Kramps M, McInnis M, Ochner CN
JournalJ Prev Alzheimers Dis
Date Published2014

BACKGROUND: Internet-based educational interventions may be useful for impacting knowledge and behavioral change. However, in AD prevention, little data exists about which educational tools work best in terms of learning and interest in participating in clinical trials.

OBJECTIVES: Primary: Assess effectiveness of interactive webinars vs. written blog-posts on AD prevention learning. Secondary: Evaluate the effect of AD prevention education on interest in participating in clinical trials; Assess usability of, and user perceptions about, an online AD education research platform; Classify target populations (demographics, learning needs, interests).

DESIGN: Observational.

SETTING: Online.

PARTICIPANTS: Men/Women, aged 25+, recruited via

INTERVENTION: Alzheimer's Universe ( education research platform.

MEASUREMENTS: Pre/post-test performance, self-reported Likert-scale ratings, completion rates.

RESULTS: Over two-weeks, 4268 visits were generated. 503 signed-up for a user account (11.8% join rate), 196 participated in the lessons (39.0%) and 100 completed all beta-testing steps (19.9%). Users randomized to webinar instruction about AD prevention and the stages of AD demonstrated significant increases (p=0.01) in pre vs. post-testing scores compared to blog-post intervention. Upon joining, 42% were interested in participating in a clinical trial in AD prevention. After completing all beta-test activities, interest increased to 86%. Users were primarily women and the largest category was children of AD patients. 66.3% joined to learn more about AD prevention, 65.3% to learn more about AD treatment.

CONCLUSIONS: Webinar-based education led to significant improvements in learning about AD prevention and the stages of AD. participation more than doubled interest in AD prevention clinical trial participation. Subjects were quickly and cost-effectively recruited, and highly satisfied with the AD education research platform. Based on these data, we will further refine prior to public launch and aim to study the effectiveness of 25 interactive webinar-based vs. blog-post style lessons on learning and patient outcomes, in a randomized, within-subjects design trial.

Alternate JournalJ Prev Alzheimers Dis
PubMed ID28529932
PubMed Central IDPMC5434756
Grant ListUL1 TR000457 / TR / NCATS NIH HHS / United States

Weill Cornell Medicine Neurology 525 E. 68th St.
PO Box 117
New York, NY 10065 Phone: (212) 746-6575