| Title | [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)]. |
| Publication Type | Journal Article |
| Year of Publication | 1975 |
| Authors | Isaac O, Thiemer K |
| Journal | Arzneimittelforschung |
| Volume | 25 |
| Issue | 9 |
| Pagination | 1352-4 |
| Date Published | 1975 Sep |
| ISSN | 0004-4172 |
| Keywords | Dose-Response Relationship, Drug, Hemoglobins, Hydrogen-Ion Concentration, In Vitro Techniques, Methods, Pepsin A, Plants, Medicinal, Sesquiterpenes, Spectrophotometry, Ultraviolet, Trichloroacetic Acid, Tyrosine |
| Abstract | (--)-alpha-Bisabolol has a primary antipeptic action depending on dosage, which is not caused by an alteration of the pH-value. The proteolytic activity of pepsin is reduced by 50 percent through addition of bisabolol in the ratio of 1/0.5. The antipeptic action of bisabolol only occurs in case of direct contact. In case of a previous contact with the substrate, the inhibiting effect is lost. |
| Alternate Journal | Arzneimittelforschung |
| PubMed ID | 21 |