HaNDL Syndrome Presenting with Thunderclap Headache.

TitleHaNDL Syndrome Presenting with Thunderclap Headache.
Publication TypeJournal Article
Year of Publication2021
AuthorsParasram M, Malhotra A, Yoo AS, Mir SA
JournalCase Rep Neurol Med
Date Published2021

Introduction: Transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) is defined as a secondary, nonvascular headache disorder characterized by the findings described in its name. Patients with HaNDL syndrome typically present with gradual onset migrainous headaches of moderate to severe intensity with transient neurological symptoms. Case Report. We discuss a patient who presented with thunderclap headache, recent transient neurologic deficits, and was ultimately diagnosed with HaNDL after an extensive neurologic evaluation.

Conclusion: Thunderclap headache has very rarely been described in patients with HaNDL. After excluding emergent and secondary causes, HaNDL should be considered in patients with thunderclap-quality headaches, particularly when there is a history of transient neurological symptoms.

Alternate JournalCase Rep Neurol Med
PubMed ID34194857
PubMed Central IDPMC8184320

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