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Prevalence of pain in atypical parkinsonism: a systematic review and meta-analysis.

TitlePrevalence of pain in atypical parkinsonism: a systematic review and meta-analysis.
Publication TypeJournal Article
Year of Publication2019
AuthorsRana AQayyum, Qureshi ARehman, Siddiqui O, Sarfraz Z, Rana R, Shtilbans A
JournalJ Neurol
Volume266
Issue9
Pagination2093-2102
Date Published2019 Sep
ISSN1432-1459
KeywordsCross-Sectional Studies, Humans, Multiple System Atrophy, Pain, Pain Management, Parkinson Disease, Parkinsonian Disorders, Prevalence, Supranuclear Palsy, Progressive
Abstract

Pain is common in atypical parkinsonism such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and dementia with Lewy bodies (LBD). In this study, a systematic review and meta-analysis was conducted and peer-reviewed literature was searched to determine the prevalence and types of pain in four atypical parkinsonism syndromes: MSA, PSP, CBD and LBD. The results show that pain was prevalent mainly in MSA patients in comparison to PSP and CBD patients. Pain was reported at an early stage and was found in females, with limb pain being the most common, followed by neck and back pain. In comparison to PSP, pain locations were similar to MSA patients. CBD patients experienced pain the least in comparison to MSA, PSP and LBD patients.

DOI10.1007/s00415-018-9049-7
Alternate JournalJ. Neurol.
PubMed ID30238268

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