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Thrombolysis for Acute Ischemic Stroke Following Transcatheter Aortic Valve Replacement: Case Report and Literature Review.

TitleThrombolysis for Acute Ischemic Stroke Following Transcatheter Aortic Valve Replacement: Case Report and Literature Review.
Publication TypeJournal Article
Year of Publication2020
AuthorsMalhotra A, Segal AZ
JournalNeurologist
Volume25
Issue2
Pagination26-27
Date Published2020 Mar
ISSN2331-2637
Abstract

INTRODUCTION: Intravenous thrombolytic therapy with recombinant tissue type plasminogen activator (IV-tPA) is the first-line treatment option for acute ischemic stroke (AIS). The tPA exclusion criteria, defined decades ago, require updates as new technologies emerge. Transcatheter aortic valve replacement (TAVR), which has begun to replace open surgery, poses a risk for acute stroke and falls outside of prior tPA guidelines.

CASE REPORT: Here we describe a post-TAVR patient treated safely with IV-tPA for presumed AIS.

CONCLUSION: Previously undescribed, we suggest that tPA should be considered for post-TAVR AIS patients who otherwise satisfy inclusion and exclusion criteria.

DOI10.1097/NRL.0000000000000260
Alternate JournalNeurologist
PubMed ID32132496

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